This medication may interfere with certain lab tests (such as thyroid function tests, creatinine level), possibly causing false test results. This document does not contain all possible drug interactions. This medication may harm an unborn or breastfeeding baby. Women who are pregnant or breastfeeding must avoid contact with this medication. If you notice symptoms in a woman such as changes in body hair or a large increase in acne, talk to her doctor and your doctor right away. This medication can affect fertility in males. In children, it may affect bone growth. Long-term clinical safety trials have not been conducted to assess the cardiovascular outcomes of testosterone replacement therapy in men. Evaluate patients who report symptoms of pain, edema, warmth and erythema in the lower extremity for DVT and those who present with acute shortness of breath for PE. Children and women should avoid contact with unwashed or unclothed application sites in men using FORTESTA see DOSAGE AND ADMINISTRATION, Use In Specific Populations, and CLINICAL PHARMACOLOGY. It is used for hormone replacement in men who are not able to produce enough testosterone (hypogonadism). To decrease this risk, carefully follow all directions for the proper use of this drug. Children should avoid contact with any unwashed or unclothed area where the medication has been applied. RxList does not provide medical advice, diagnosis or treatment. Dose titrations on Days 14, 35, and 60 resulted in mean (SD) Cavg and Cmax for final doses of 10 mg to 70 mg on Day 90 shown in Table 5. The percentages of patients with Cmax greater than 1500 ng/dL, and between 1800 and 2499 ng/dL on Day 90 were 5.4% and 1.6%, respectively. The secondary endpoint was the percentage of patients with Cmax above 3 pre-determined limits. Free thyroid hormone concentrations remain unchanged, however, and there is no clinical evidence of thyroid dysfunction. Edema, with or without congestive heart failure, may be a serious complication in patients with preexisting cardiac, renal, or hepatic disease see ADVERSE REACTIONS. Androgens, including FORTESTA, may promote retention of sodium and water. Long-term therapy with testosterone enanthate has produced multiple hepatic adenomas. However, testosterone levels may be in the normal or subnormal range in men abusing synthetic testosterone derivatives. Testosterone has been subject to abuse, typically at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids. Wait a few minutes for the application site to dry completely before dressing. The dosage is based on your medical condition, lab tests, and response to treatment. Do not let others apply this medication to your body. Use one finger to rub the gel in evenly.
